QRTI Newsline --- Wednesday September 8, 2010

Government takes action against frauds

By Rochelle L. Goodson

Within the last several months, Health and Human Services Department's Office of Research Integrity issued a significant number of notices in the Federal Register that identify cases of scientific fraud and misconduct. Each notice also include the sanction(s) associated with the allegations of fraud in each case. Fraudulent research, whether in industry or federally sponsored trials, has the potential to jeopardize the safety of human subjects in clinical trials and ultimately the public health.

A read through of these cases provides some insight of the range of the types of fraudulent activity that are possible. There are examples of altering, falsifying, and fabricating data, (Lieber) as well as, substituting human blood specimens of study subjects with normal specimens. (Bryant and Layman) Ongoing oversight programs by both government and industry continue to offer the means and methods that identify scientific misconduct and/or fraud. However, these instances of egregious research activities also underscore the ongoing need for training clinical research professionals to not only familiarize themselves with various fraudulent methods, but to recognize and implement measures that emphasize prevention of scientific misconduct.



1. Findings of Research Misconduct
NOTICES: Lieber, James David,

Published: 2007-07-23
Notice is hereby given that the Office of Research Integrity (ORI) and the Assistant Secretary for Health have taken final action in the following case: James David Lieber, University of California at Los Angeles: Based on the findings of an inquiry report by the University of California at Los Angeles (UCLA) and additional analysis



2. Findings of Scientific Misconduct
NOTICES: Bryant, Joy,

Published: 2007-06-25
Notice is hereby given that the Office of Research Integrity (ORI) and the Assistant Secretary for Health have taken final action in the following case: Joy Bryant, University of Oklahoma Health Sciences Center: Based on the report of an investigation conducted by the University of Oklahoma Health Sciences Center (OUHSC) and additional analysis



3. Findings of Scientific Misconduct
NOTICES: Layman, Diana,

Published: 2007-06-25
Notice is hereby given that the Office of Research Integrity (ORI) and the Assistant Secretary for Health have taken final action in the following case: Diana Layman, University of Oklahoma Health Sciences Center: Based on the report of an investigation conducted by the University of Oklahoma Health Sciences Center (OUHSC) and additional



DEPARTMENT OF HEALTH AND HUMAN SERVICES : Health and Human Services Department

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